Completed Studies

  • The Coma Family Program (COMA-F): A Multi-Site Clinical Trial of a Resilience Program for Caregivers of Patients with Severe Acute Brain Injury (R01AG098476)

    Principal Investigator: Alexander Presciutti, PhD, MSCS Funding Source: National Institute on Aging

  • Development of a Mind Body Program to Reduce Cartilage Breakdown and Knee Pain in Obese Osteoarthritis Patients With Co-Morbid Depression (R34AT010370)

    Principal Investigators:
    Ana-Maria Vranceanu, PhD & Cale Jacobs, PhD
    Funding Source:
    National Center for Complementary and Integrative Health

  • First Year of Multiple Sclerosis in the MS Dyad

    Principal Investigators: Heena Manglani, PhD
    Study Coordinator: Anastasia Prussakova; Ariel Emrani Funding Source: International Neuropalliative Care Society

  • Improving Multimodal Physical Function in Adults with Heterogenous Chronic Pain

    Principal Investigators: Ana‑Maria Vranceanu, PhD; Jonathan Greenberg, PhD
    Study Coordinator: Dany La Camera, BA Funding Source: NCCIH

  • INSTILL: Interventions for Stressful Transitions in Later Life

    Principal Investigators: Evan Plys, PhD
    Study Coordinator: Makenna Law, BS & Morgan Seward, BA
    Funding Source: The Ki Sub Joung Innovative Junior Faculty Pilot Award in Aging and Palliative Care (MGH Internal)

    This study will build partnerships with skilled nursing facilities and establish a community advisory board to co-design a psychosocial intervention for older adults receiving nursing home-based post-acute rehabilitation care as well as their family care-partners (i.e., family dyads), with an emphasis on socioeconomically under-resourced families. We will (1) conduct qualitative interviews with Medicaid-eligible older adults and their family care-partners skilled nursing facilities to identify psychosocial treatment preferences; (2) conduct focus groups with skilled nursing facility staff to identify workflows for psychosocial intervention; and (3) convene a community advisory board of clinicians and other persons with relevant lived experience to collaboratively develop an intervention for family dyads in skilled nursing facilities.

  • Integrating Mind-Body Skills With Physical Activity to Improve Physical and Emotional Outcomes in Patients with Heterogeneous Chronic Pain (3R34AT009356-02S1)

    Principal investigator: 
    Ana-Maria Vranceanu, PhD
    Funding Source: 
    National Center for Complementary and Integrative Health

  • In Need and Hard to Reach: Adaptation of an Evidence-based Neurofibromatosis Resiliency Training Program for Web-Based Delivery (NF-WEB)

    Principal investigator:
    Ethan Lester, PhD, Ana-Maria Vranceanu, PhD
    Funding Source:
    NF Northeast, NF Midwest, NF Texas

  • MASC: The Mindful and Self-Compassionate Care Program; Reducing Stress for Caregivers of Persons with Dementia (1R01AG078204-01)

    Principal Investigators: Christina Ritchie, MD, MSPH & Ana-Maria Vranceanu, PhD
    Study Coordinator: Aniyah Travis, BA Funding Source: National Institute on Aging

  • My Healthy Brain: A Mindfulness-Based Lifestyle Intervention to Modify Early Risk of Dementia in Older Adults (1K23AG075257-01)

    Principal Investigator: Ryan Mace, PhD
    Study Coordinator:Makenna Law, BS
    Funding source: National Institute on Aging

    This K23 project will establish the feasibility of a mindfulness-based lifestyle program, My Healthy Brain (MHB), to modify multiple risk factors dementia in older adults with subjective cognitive decline. We will conduct focus groups with medical stakeholders(N = 20) and a feasibility randomized clinical trial (RCT) of the MHB program (N = 50). This data will inform a larger efficacy trial of the MHB program, which we hope to scale with mobile health technology to widely engage older adults in healthy lifestyles with aging.

    For more information, please contact Makenna Law (mlaw@mgh.harvard.edu)

  • My Healthy Brain: A Novel Mind-Body Program for Promoting Brain Health Through Lifestyle Change (2020A013107)

    Principal Investigators:
    Ana-Maria Vranceanu, PhD, Ryan Mace, PhD
    Funding Source:
    Osher Center for Integrative Medicine

  • Physical and Psychological Measures of Pain in Acute Orthopedic Injuries: Use of At-Home Virtual Reality (recoVR)

    Principal Investigator: 
    Ryan Mace, PhD
    Funding Source: 
    The David Borsook Project and the Cathedral Fund

  • Psychophysical and Neural Mechanisms Contributing to Chronic Postsurgical Pain in Adolescents and Adults

    Principal Investigator: Christine B. Sieberg, PhD, EdM, MA Study Clinician: Christine B. Sieberg, PhD, EdM, MA Study Coordinators: Caitlin Curry, BA Study Post Doctoral Fellow: Ziyan Wu, PhD Funding Source: National Institute of General Medical Sciences

  • Risk and Resiliency Factors in Parents of Children Admitted to the Neonatal Intensive Care Unit: a Prospective Study

    Principal investigator:
    Victoria Grunberg, PhD

  • Recovering Together After Cardiac Arrest: a Dyadic Mind-body Intervention for Emotional Distress in Cardiac Arrest Survivors and Their Informal Caregivers (K23AT012487)

    Principal Investigator: Alexander Presciutti, PhD, MSCS Study Coordinator: Sara Bogan, BS Funding Source: National Center for Complementary and Integrative Health

  • Resilient Together: Developing a Resiliency Skills Program for Dyads of Patients With Young Onset Dementia and Their Care-Partners (R21NR017979-02S1)

    Principal investigator:
    Ana-Maria Vranceanu, PhD
    Funding Source:
    National Institute of Nursing Research

  • Resilient Families (R‑FAM): A Dyadic Resiliency Intervention for Parents of Babies in Neonatal Intensive Care

    Principal Investigators: Victoria Grunberg, PhD
    Study Coordinator: Julia Davis Funding Source: NICHD

  • Resiliency Training for Adults with Neurofibromatosis via Live Videoconferencing (W81XWH-17-1-0121)

    Principal investigator: 
    Ana-Maria Vranceanu, PhD
    Funding Source: 
    Department of Defense

  • STRIDE: Using Mobile Technology to Reduce Stress in Caregivers of Persons with Dementia. A Scalable Solution to A Growing Problem

    Principal Investigators: Ana‑Maria Vranceanu, PhD; Jennifer Huberty, PhD
    Study Coordinator: Morgan Seward, BA Funding Source: National Institute on Aging

  • TEND: Toolkit for Experiential Well‑being in Dementia

    Principal Investigators: Christine Ritchie, MD, MSPH; Ana‑Maria Vranceanu, PhD
    Study Coordinator: Elizabeth Rochon, BA; Ayush Thacker, BS‍ ‍ Funding Source: Robert Wood Johnson Foundation

  • Toolkit for Optimal Recovery After Orthopedic Injury: A Multi-Site Feasibility Study to Prevent Persistent Pain and Disability (1U01AT010462-01A1)

    Principal Investigator: 
    Ana-Maria Vranceanu, PhD
    Funding Source: 
    National Center for Complementary and Integrative Health

  • Toolkit: Live Video Mind‑Body Treatment to Prevent Persistent Symptoms Following MTBI

    Principal Investigators: Jonathan Greenberg, PhD
    Study Coordinator: Kozbi Bayne-Cliff, BS Funding Source: National Center for Complementary and Integrative Health

  • Understanding the Needs of Caregivers of Comatose ICU Patients

    Principal Investigator: 
    David Hwang, PhD & Ana-Maria Vranceanu, PhD
    Funding Source:
    Yale Departmental Funding

  • Understanding the Interplay Between Lifestyle Factors and Emotional Distress for Survivors with Hemorrhagic Stroke and Their Informal Caregivers: A Mixed Methods Dyadic Natural History Study

    Principal Investigator: 
    Ethan Lester, PhD
    Funding Source: 
    Young Investigator Award Heitman Fellowship (MGH Neurology Internal Research Grant)

  • Web-Based Mind-Body Treatment to Enhance Resilience Among Patients With Painful Nontraumatic Upper Extremity Conditions and Comorbid Depression

    Principal Investigator: 
    Jafar Bakhshaie, MD, PhD
    Funding Source: 
    Kaplen Fellowship & Livingston Fellowship Award